A virtual sensor for electric vehicles’ state of charge estimation

The estimation of the state of charge is a critical function in the operation of electric vehicles. The battery management system must provide accurate information about the battery state, even in the presence of failures in the vehicle sensors. This article presents a new methodology for the state of charge estimation (SOC) in electric vehicles without the use of a battery current sensor, relying on a virtual sensor, based on other available vehicle measurements, such as speed, battery voltage and acceleration pedal position. The estimator was derived from experimental data, employing support vector regression (SVR), principal component analysis (PCA) and a dual polarization (DP) battery model (BM). It is shown that the obtained model is able to predict the state of charge of the battery with acceptable precision in the case of a failure of the current sensor

Manifesting Unobtainable Secrets: Threshold Elliptic Curve Key Generation using Nested Shamir Secret Sharing

We present a mechanism to manifest unobtainable secrets using a nested Shamir secret sharing scheme to create public/private key pairs for elliptic curves. A threshold secret sharing scheme can be used as a decentralised trust mechanism with applications in identity validation, message decryption, and agreement empowerment. Decentralising trust means that there is no single point vulnerability which could enable compromise of a system. Our primary interest is in twisted Edwards curves as used in EdDSA, and the related Diffie-Hellman key-exchange algorithms. The key generation is also decentralised, so can be used as a decentralised secret RNG suitable for use in other algorithms. The algorithms presented could be used to fill a ``[TBS]'' in the draft IETF specification ``Threshold modes in elliptic curves'' published in 2020 and updated in 2022

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies.

Mitochondrial dysfunction has long been implicated in the neurodegenerative disorder Parkinson's disease (PD); however, it is unclear how mitochondrial impairment and α-synuclein pathology are coupled. Using specific mitochondrial inhibitors, EM analysis, and biochemical assays, we report here that intramitochondrial protein homeostasis plays a major role in α-synuclein aggregation. We found that interference with intramitochondrial proteases, such as HtrA2 and Lon protease, and mitochondrial protein import significantly aggravates α-synuclein seeding. In contrast, direct inhibition of mitochondrial complex I, an increase in intracellular calcium concentration, or formation of reactive oxygen species, all of which have been associated with mitochondrial stress, did not affect α-synuclein pathology. We further demonstrate that similar mechanisms are involved in amyloid-β 1-42 (Aβ42) aggregation. Our results suggest that, in addition to other protein quality control pathways, such as the ubiquitin-proteasome system, mitochondria per se can influence protein homeostasis of cytosolic aggregation-prone proteins. We propose that approaches that seek to maintain mitochondrial fitness, rather than target downstream mitochondrial dysfunction, may aid in the search for therapeutic strategies to manage PD and related neuropathologies.Infinitus China Ltd

Concordancia diagnóstica entre Atención Primaria y Salud Mental.

tención Primaria (AP) y Salud Mental (SM). Metodología. Estudio descriptivo y retrospectivo realizado en el Centro de SM de Villaverde, Madrid, España. La muestra está conformada por 1050 pacientes adultos nuevos consecutivos derivados desde AP a SM desde enero a diciembre del año 2016. Se registraron las siguientes variables: Centro de AP de origen de la derivación, edad, sexo, tipo de actividad solicitante en la derivación (Psiquiatría o Psicología), diagnóstico establecido por AP y diagnóstico establecido por SM. Resultados. La concordancia diagnóstica entre AP y SM presentó un coeficiente de kappa global de 0,383 (IC 95 % 0,333-0,433). Los grupos diagnósticos con menor concordancia fueron el trastorno adaptativo (kappa: 0,200), el trastorno de ansiedad (kappa: 0,242) y el trastorno afectivo depresivo (kappa: 0,340). Los grupos diagnósticos con mayor concordancia fueron el trastorno bipolar (kappa: 0,816) y el trastorno psicótico (kappa: 0,689). El trastorno adaptativo fue el diagnóstico más frecuentemente diagnosticado en SM entre los no coincidentes con AP (38,99 %). Conclusiones. La concordancia diagnóstica entre AP y SM es baja, lo cual podría afectar a la calidad asistencial ofrecida a los pacientes. Se considera necesario el planteamiento de nuevas estrategias que permitan aumentar esta concordancia.post-print143 K

Funerary Artifacts, Social Status, and Atherosclerosis in Ancient Peruvian Mummy Bundles

Background: Evidence of atherosclerotic plaques in ancient populations has led to the reconsideration of risk factors for heart disease and of the common belief that it is a disease of modern times. Methods: Fifty-one wrapped mummy bundles excavated from the sites of Huallamarca, Pedreros, and Rinconada La Molina from the Puruchuco Museum collection in Lima, Peru, were scanned using computed tomography to investigate the presence of atherosclerosis. Funerary artifacts contained within the undisturbed mummy bundles were analyzed as an attempt to infer the social status of the individuals to correlate social status with evidence of heart disease in this ancient Peruvian group. This work also provides an inventory of the museum mummy collection to guide and facilitate future research. Results: Statistical analysis concluded that there is little association between the types of grave goods contained within the bundles when the groups are pooled together. However, some patterns of artifact type, material, atherosclerosis, and sex emerge when the 3 excavation sites are analyzed separately. Conclusions: From the current sample, it would seem that social class is difficult to discern, but those from Huallamarca have the most markers of elite status. We had hypothesized that higher-status individuals may have had lifestyles that would place them at a higher risk for atherogenesis. There seems to be some indication of this within the site of Huallamarca, but it is inconclusive in the other 2 archeological sites. It is possible that a larger sample size in the future could reveal more statistically significant results

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011

Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

Measurements are presented of production properties and couplings of the recently discovered Higgs boson using the decays into boson pairs, H →γ γ, H → Z Z∗ →4l and H →W W∗ →lνlν. The results are based on the complete pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV, corresponding to an integrated luminosity of about 25 fb−1. Evidence for Higgs boson production through vector-boson fusion is reported. Results of combined fits probing Higgs boson couplings to fermions and bosons, as well as anomalous contributions to loop-induced production and decay modes, are presented. All measurements are consistent with expectations for the Standard Model Higgs boson

Measurement of the top quark pair cross section with ATLAS in pp collisions at √s=7 TeV using final states with an electron or a muon and a hadronically decaying τ lepton

A measurement of the cross section of top quark pair production in proton-proton collisions recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 7 TeV is reported. The data sample used corresponds to an integrated luminosity of 2.05 fb -1. Events with an isolated electron or muon and a τ lepton decaying hadronically are used. In addition, a large missing transverse momentum and two or more energetic jets are required. At least one of the jets must be identified as originating from a b quark. The measured cross section, σtt-=186±13(stat.)±20(syst.)±7(lumi.) pb, is in good agreement with the Standard Model prediction